Agios Pharmaceuticals Founder and Advisor Publish in Nature Genetics on Further Links Between Serine Metabolic Pathway and Cancer

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Agios Pharmaceuticals, the leading biopharmaceutical company focused on discovering and developing novel drugs in the rapidly emerging field of cancer metabolism, announced today a publication from Agios founder Lewis C. Cantley, Ph.D., and Agios advisor Matthew Vander Heiden, M.D., Ph.D., in the journal Nature Genetics that adds to evidence that dysregulated activity of the serine pathway is linked to the growth and survival of certain cancers. An independent study recently published in the journal Nature by the Whitehead Institute and Agios scientists also concluded that the serine pathway may play an important role in certain breast cancers. The new findings were generated using a novel research method called metabolic flux analysis, which may have broad application in cancer metabolism research for identification of new cancer targets.