CAMBRIDGE, Mass.--(BUSINESS WIRE)--Alnylam Pharmaceuticals, Inc. (Nasdaq: ALNY), a leading RNAi therapeutics company, today announced the publication of new data in the journal Nature Biotechnology by Alnylam scientists and collaborators from Tekmira Pharmaceuticals Corporation, AlCana Technologies, Inc., and The University of British Columbia (UBC). The new study employed a rational design approach for the discovery of novel lipids that can be incorporated into lipid nanoparticles (LNPs) for systemic delivery of RNAi therapeutics. This new research complements the combinatorial chemistry-based approach recently described by Alnylam scientists in the Proceedings of the National Academy of Sciences (PNAS) (Love et al. (January 11, 2010) Proc. Natl Acad. Sci. USA, 10.1073/pnas.0910603106), and highlights the power of using multiple parallel approaches for optimizing LNPs.
