CHESHIRE, Conn.--(BUSINESS WIRE)--Alexion Pharmaceuticals, Inc. (Nasdaq: ALXN) today announced the presentation of interim results from the first Phase I/II trial of samalizumab, the company’s investigational, first-in-class humanized monoclonal antibody. The ongoing trial is evaluating the safety, maximum tolerated dose, pharmacokinetics, and pharmacodynamics of samalizumab in adult patients with advanced stage B-cell chronic lymphocytic leukemia (B-CLL) or multiple myeloma (MM). Data presented today at the 52nd American Society of Hematology (ASH) Annual Meeting and Exposition in Orlando indicate that samalizumab was well tolerated at all doses studied, exhibited a dose-dependent biological and pharmacokinetic response, and exhibited initial evidence of anti-tumor activity. (1)
