A large-scale international study involving French researchers from the Inserm-Institut Pasteur Lille-Université Lille Nord de France “Public health and molecular epidemiology of ageing-related diseases” joint research unit led by Philippe Amouyel, has just discovered a gene for susceptibility to a rare disease that causes susceptibility to a common one, Alzheimer’s disease, providing evidence of the heterogeneous aetiology of Alzheimer’s disease. This whole-exome sequencing approach is explained in detail in The New England Journal of Medicine dated 14 November 2012.
