CAMBRIDGE, Mass.--(BUSINESS WIRE)--Xanthus Pharmaceuticals, Inc. today announced that the company has acquired an exclusive worldwide license to a patent estate from Johns Hopkins University for treating immune-related disorders by inhibiting the FLT3 tyrosine kinase. FLT3 is highly expressed on dendritic cells, which are responsible for the stimulation of T cells. In preclinical studies conducted by Johns Hopkins researchers, FLT3 signaling modulated autoimmune responses, suggesting that inhibition of the FLT3 pathway may reverse the course and severity of autoimmune disease.
