VANCOUVER, BC--(Marketwire - January 03, 2008) - Upstream Biosciences Inc. (OTCBB: UPBS) today announced that it has entered into a collaboration with the Provincial Laboratory for Public Health (or ProvLab) in Alberta, Canada to begin in vitro testing of Upstream’s novel compounds for the potential treatment of malaria. According to the World Health Organization (WHO), an estimated 500 million people become severely ill with malaria and more than one million people die of the disease each year.