NORTH BRUNSWICK, N.J.--(BUSINESS WIRE)--The U.S. Patent and Trademark Office has approved Advaxis, Inc., (OTCBB: ADXS), the live, attenuated Listeria monocytogenes (Listeria) immunotherapy company, intellectual property protection to patent application 11/223,945 – a live, attenuated Listeria vaccine that secretes novel fragments of the tumor antigen HER2/neu (human epidermal growth factor receptor 2), when using the company’s proprietary listeriolysin O (LLO) fusion platform technology. The patent also extends protection to LLO-HER2/neu proteins independent of live Listeria which can be used as protein vaccines.
