Tripos Announces Initial Minimum Liquidating Distribution of $0.47 per Share Payable Nov. 13, 2007; $3.9 Million to Be Transferred to Liquidating Trust

ST. LOUIS--(BUSINESS WIRE)--Tripos, Inc. (OTCBB:TRPS), announced today that its board of directors has authorized a minimum initial liquidating distribution of $0.47 per share. Absent any unexpected developments, the initial distribution will be payable in cash beginning on Nov. 13, 2007, to shareholders of record on Nov. 8, 2007. The initial distribution is subject to increase based upon the results of continuing efforts to finalize Tripos’ net assets available for liquidation. To receive payment, shareholders must submit their stock certificates, together with a properly executed letter of transmittal, to Tripos’ transfer agent.

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