A simple and non-invasive method to detect cancer-related mutations without direct biopsy sampling of tumors has been developed by A*STAR researchers.
The technique uses a tailor-made filter to collect cancer cells circulating in the bloodstream after being shed from the tumor mass. These circulating cells can serve as a liquid biopsy. The study was led by Min-Han Tan and Jackie Y. Ying from the Institute of Bioengineering and Nanotechnology (IBN) of A*STAR, with collaborators from the Genome Institute of Singapore of A*STAR and other research centers in Singapore.
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