24-h pH monitoring and esophageal manometry are the gold standards of methods used for diagnosing GER and esophageal motor disorders, respectively. Intraluminal refluxate can be recognized by US images. Sonographic GER diagnosis is made by backward movement of gastric content into the esophagus and the visualization of the clearance of refluxate material. Postprandial refluxate was seen in 45 of 500 (9%) adults. GER and/or manometric pathology was found in 71.1% of the refluxate positive patients.