Thermo Fisher Scientific Release: Innovations Address Range Of Applications Across Biopharmaceutical Workflow

UHPLC, protein analysis kits and columns among highlights at AAPS 2015

ORLANDO--(BUSINESS WIRE)--AAPS 2015 – New technologies for a range of biopharmaceutical applications will be showcased this week at the American Association of Pharmaceutical Scientists Annual Meeting, October 25-29, 2015 at the Orlando County Convention Center, Booth #1911.

“The Vanquish Flex offers us a range of powerful detectors, which adds significantly to our chromatography toolkit.”

“Biopharmaceutical manufacturers are looking to accelerate the development pipeline while increasing efficiency and minimizing costs,” said John Rontree, director of vertical marketing, biopharma, Thermo Fisher Scientific. “We have a deep understanding of these challenges and innovate solutions at every stage of the biopharma process – from discovery to bioproduction to QA-QC.”

Designed for the biopharmaceutical market, the new Thermo Scientific Vanquish Flex UHPLC system delivers exceptional performance and reliable separations with the flexibility required for labs developing methods ranging from high-throughput analyses to pharmaceutical quality control applications. The Vanquish Flex is designed for high speed, resolution and sensitivity, allowing researchers who perform biocompatibility analysis to obtain high quality and consistent data. By incorporating an integrated modular design, customers have the ability to mix and match modules depending on the demands of the application.

The National Institute for Bioprocessing Research and Training (NIBRT), a training facility in Dublin, Ireland, trains more than 90 percent of leading biopharmaceutical manufacturing companies. The facility is conducting a range of tests using the Vanquish Flex UHPLC including peptide mapping, glycan analysis, intact protein analysis and others. “At NIBRT, we push the analytical capabilities of our instruments very hard,” said Dr. Jonathan Bones, Principal Investigator, NIBRT. “The Vanquish Flex offers us a range of powerful detectors, which adds significantly to our chromatography toolkit.”

The new Thermo Scientific SMART Digest kit is a protein analysis kit designed for biopharmaceutical applications that require highly reproducible, sensitive and fast bottom-up analyses of proteins in high-throughput workflows. Designed to minimize preparation time and variability, the SMART Digest kit facilitates fast and reliable analytical results using a simple three-step, easy-to-implement process that can be automated. Its immobilized trypsin design is formulated for high-quality data with significantly reduced sample preparation time compared to traditional in-solution digestion methods.

The Thermo Scientific MAbPac RP column is designed for analytical chemists requiring high-resolution accurate mass determination of intact proteins, such as monoclonal antibody (mAb) variants, antibody drug conjugates (ADCs), as well as those conducting high-resolution mass spectrometric analysis of mAbs and mAb fragments. This addresses the increased need for reliable and rapid characterization of these compounds required for upstream biopharmaceuticals development. The MAbPac RP column has been optimized for MS and UV detection: its thermal and pH stability yields promote consistent separations, while the polymeric resin has a pore size that is optimal for mAbs.

Also at AAPS, Thermo Fisher will also present a series of Vendor Seminars on Monday, October 26^th, 9 am – 12 pm:

• Separation of Monoclonal Antibody and Antibody Drug Conjugates
• Workflows for Monoclonal Antibody Characterization
• How to Improve your Peptide Quantitation Workflow to Provide Greater Speed and Reproducibility
• No More Unknowns: A Complete Analytical Workflow for Extractable and Leachable Impurities

For more information about Thermo Fisher Scientific at AAPS, please visit here.

About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. is the world leader in serving science, with revenues of $17 billion and approximately 50,000 employees in 50 countries. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services – we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive support. For more information, please visit http://www.thermofisher.com.

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