Takeda Pharmaceuticals North America, Inc. Release: ACTOS(R) (Pioglitazone HCl) Demonstrates Significant Improvements In Cardiovascular Outcomes For High-Risk Patients With Type 2 Diabetes

COPENHAGEN, DENMARK -- (MARKET WIRE) -- September 14, 2006 -- Several abstracts presented today at the 42nd Annual Meeting of the European Association for the Study of Diabetes (EASD) indicated that ACTOS® (pioglitazone HCl), an oral antidiabetic medication, demonstrated significant cardiovascular benefits such as reducing the risk of heart attack and/or stroke and acute coronary syndrome in patients with type 2 diabetes. Cardiovascular disease (CVD) is the leading cause of premature death in patients with diabetes. An estimated 171 million people worldwide have diabetes, and CVD is responsible for 50% to 80% of deaths in people with diabetes.

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