Symphogen A/S And Biovitrum AB Initiate Phase 1 Clinical Trial with the First Recombinant Polyclonal Antibody to Enter Clinical Evaluation

COPENHAGEN, Denmark & STOCKHOLM, Sweden--(BUSINESS WIRE)--Symphogen and Biovitrum today announced the initiation of a Phase 1 clinical trial to test the safety, pharmacokinetics and pharmacodynamics of Sym001 (Anti-RhD) in healthy volunteers. Sym001 is a recombinant, polyclonal antibody product candidate, comprised of 25 different anti-Rhesus D antibodies. Sym001 is in development for the treatment of Idiopathic Thrombocytopenic Purpura (ITP) and for the prevention of Hemolytic Disease of the Newborn (HDN). Symphogen and Biovitrum are jointly developing Sym001 under a co-development and commercialization agreement announced in February 2006.

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