After the worldwide alarm triggered by 2003’s SARS outbreak, it might seem reckless to set about creating a potentially far more devastating virus in the lab. But that is what is being attempted by some researchers, who argue that the dangers of doing nothing are even greater.We already know that the H5N1 bird flu virus ravaging poultry farms in Asia can be lethal on the rare occasions when it infects people. Now a team is tinkering with its genes to see if it can turn into a strain capable of spreading from human to human. If they manage this, they will have created a virus that could kill tens of millions if it got out of the lab.