SGX Pharmaceuticals, Inc. To Present At Two Upcoming Investor Conferences

SAN DIEGO, Nov. 2 /PRNewswire-FirstCall/ -- SGX Pharmaceuticals, Inc. announced today that the company will be presenting at two upcoming investor conferences during which Mike Grey, president & chief executive officer of SGX Pharmaceuticals, will provide a corporate overview on the Company’s oncology pipeline. The conference information is as follows:

* CIBC 17th Annual Healthcare Conference Presentation: Wednesday, November 8, 2006 at 2:25 PM Eastern Standard Time at the Waldorf Astoria Hotel in New York City. * Rodman & Renshaw 8th Annual Healthcare Conference Presentation: Wednesday, November 8, 2006 at 4:30 PM Eastern Standard Time at the New York Palace Hotel, New York City.

A live webcast of the Rodman & Renshaw presentation will be available under the investor relations section of the Company’s website at www.sgxpharma.com. Replays of the presentation will be available for 90 days following the event. Please connect to the Company’s website several minutes prior to the start of the broadcast to ensure adequate time for any software download that may be necessary.

About SGX Pharmaceuticals

SGX Pharmaceuticals is a biotechnology company focused on the discovery, development and commercialization of innovative cancer therapeutics. SGX’s oncology pipeline includes Troxatyl as well as drug candidates from its enabling, proprietary FAST(TM) drug discovery platform, such as next generation BCR-ABL inhibitors currently being developed in partnership with Novartis, and MET tyrosine kinase inhibitors. More information on the pipeline and drug discovery platform can be found at www.sgxpharma.com and in the Company’s various filings with the Securities and Exchange Commission.

SGX Pharmaceuticals, Inc.

CONTACT: Todd Myers, Chief Financial Officer of SGX Pharmaceuticals,+1-858-558-4850; or Media & Investor Relations, Jason Spark of PorterNovelli Life Sciences, +1-619-849-6005, for SGX Pharmaceuticals, Inc.

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