Bonn, Germany – 14th September 2011: SAW Instruments GmbH, developer of innovative biosensor technology for life sciences research in biotech and academia, will present a poster at this year’s MipTec meeting, Basel, Switzerland (20-22nd September). Entitled “Binding Kinetics of Therapeutic Antibodies to Native Proteins on Living Cells”, the new poster discusses recent work carried out in collaboration with Affimed Therapeutics AG (full abstract on SAW website). The poster provides kinetics data illustrating the interaction of one of Affimed’s therapeutic antibodies with living tumour cells, including a comparison of KD values obtained using SAW instrumentation, with values previously calculated by FACS and ELISA. The poster will be available for viewing on Thursday 22nd September, 1pm-2.30pm (Poster Number 207), with SAW personnel on hand to provide more information and further discussion.
As well as the poster, SAW will release and demonstrate the new sam®X at MipTec 2011, the latest member of the SAW biosensor product family. sam®X expands the power and flexibility of the portfolio by empowering users through workflow-driven features, including an increase in the number of sensor chips to two, providing a total of 8 channels, each of which can be addressed individually or in user-specified combinations. The sam®X will be demonstrated at booth A49, where dedicated application specialists will be providing answers to any questions and showing the system in action. Personal demonstration slots will also be available, which can be reserved before the event via the SAW website.
For more information on the innovative sam® biosensor range, visit MipTec booth A49 or see www.saw-instruments.de.
Notes on the technology
Surface Acoustic Wave technology is based on the ability of a wave of energy to travel across the surface of a material. Each surface has a typical inherent elasticity affecting the way the energy of the wave dissipates as it travels across the surface of the material being analysed. Thus, the nature of the surface in question, and therefore any changes to it, can be assessed by sensors monitoring the behaviour of the wave as it propagates across the surface. In particular, changes in mass result in alterations to the phase of the wave, whilst viscoelastic and conformational characteristics influence wave amplitude. The technology developed and employed by SAW instruments is capable of accurately interpreting this information in order to provide real time readouts measuring binding and conformational changes in the samples through which the wave passes.
About SAW Instruments GmbH
SAW Instruments GmbH designs, develops and sells biosensor-based laboratory instruments for life sciences research. The proprietary technology of SAW Instruments employs a Surface Acoustic Waves approach to biological measurement, rather than using traditional optical methods such as SPR. The technology is uniquely positioned compared to other biosensor technologies based on its ability to measure conformational changes in cells, membranes and vesicles. In addition, the system is also capable of providing other industry standard measurements including those involving kinetics, quantitation and affinity.
SAW instruments has more than ten years experience in the field of label-free biosensor technology and a number of our customers have successfully published work employing the platform. It is our goal is to continue to build on this experience, as well as to develop a family of workflow-driven products to further meet our customers’ needs.
