WAYNE, Pa.--(BUSINESS WIRE)--Safeguard Scientifics, Inc. (NYSE: SFE), a holding company that builds value in growth-stage technology and life sciences companies, today announced that it participated in the second closing of Tengion’s Series C equity financing. The second close totaled approximately $21 million. Based in East Norriton, PA with a pilot manufacturing facility in Winston-Salem, NC, Tengion is a clinical stage regenerative medicine company focused on the development of neo-organs and neo-tissues.