Safeguard Scientifics, Inc. (NYSE: SFE), a holding company that builds value in growth-stage life sciences and technology companies, today announced that its annual meeting of shareholders will be held on Thursday, May 26, 2011 at 8am EDT at Dolce Valley Forge, King of Prussia, PA. The meeting will be webcast live at www.safeguard.com/annualmeeting and available via toll-free conference call.