Roche Holding AG (ROG.VX: Quote, Profile, Research) is not interested in doing a major merger and is content with its current business portfolio, a spokesman for the Swiss drugs and diagnostics group said on Wednesday when asked if it might enter the fray for Aventis SA (AVEP.PA: Quote, Profile, Research) . “As we have always said in the past, we are fully convinced that a merger with any competitor does not make sense,” a spokesman said.