London, UK; Brentwood, TN, US; 10 June 2008 - Protherics PLC
("Protherics" or the "Company"), the international biopharmaceutical
company focused on critical care and cancer, Protherics PLC announces
the grant, on 9 June 2008, of the following options over Ordinary
Shares in Protherics ("Ordinary Shares") to Directors and other Persons
Discharging Managerial Responsibility (PDMRs) under the terms of
the Protherics PLC Long Term Incentive Plan ("LTIP"):