Ora Unveils Breakthrough Clinical Trial Innovations at ARVO 2025

BOSTON--(BUSINESS WIRE)--#ARVO--Ora, the leading global ophthalmology contract research organization (CRO), is pleased to announce our participation in the Association for Research in Vision and Ophthalmology (ARVO) 2025 Annual Meeting (May 4-8) in Salt Lake City, Utah.



This year, Ora’s scientific engagements include 2 podium presentations and 10 poster presentations highlighting innovations that advance ophthalmology clinical trials, including AI image analyses, retinal endpoints for novel therapeutics, and new technologies to measure efficacy.

“ARVO continues to set the global standard for showcasing the latest advancements in ophthalmic research, and Ora is thrilled to be part of this impactful congress in 2025 once again,” proclaimed Paul Colvin, CEO of Ora. “For over 50 years, Ora has been a trusted clinical trial partner to innovators around the globe, contributing to over 85 product approvals through the dedication of our people, the rigor of our operations, and the innovative nature of our study designs and endpoints. Our paper and poster presentations at ARVO reflect the passion, excellence, and meaningful impact of our work, highlighting our deep and enduring commitment to transforming patient outcomes for the better."

Leading Research Highlights at ARVO 2025:

  • Glaucoma Innovations:
    Dr. Gus De Moraes, world-renowned glaucoma specialist and Ora’s Chief Medical Officer, will present research leveraging ultrasound biomicroscopy (UBM) to evaluate cilioscleral interposition device (CID) implantation success and its impact on intraocular pressure (IOP). The study aims to identify predictive factors for surgical outcomes in both open- and narrow-angle glaucoma.

    “With glaucoma expected to affect over 110 million people by 2040, it's vital to innovate beyond treatment—into prediction and prevention,” said Dr. De Moraes.
  • Dry Eye Disease (DED) Breakthrough:
    Dr. Ethan Bensinger, VP at Andover Eye Institute (AEI), will unveil a novel technician-free interface for measuring visual acuity deficits in DED. The Interblink Visual Acuity Decay (IVAD) system uses pupil-core tracking to detect blinks and eye movement, allowing patients to input responses directly to streamline testing and minimizing errors.

    "The IVAD system takes dry eye patients' critical but subjective complaints of blurry vision and provides an unbiased metric of visual function," added Dr. Bensinger.

Visit Ora at Booth #1701 to experience where science, strategy, and innovation converge to shape the future of clinical trials in ophthalmology. This year marks the launch of Ora's new tagline and brand campaign: The Ophthalmology Research Company — reinforcing the company's singular focus and unmatched depth in advancing ophthalmic research. The booth will also feature insights on the human experience of blindness through The Blind Canvas Project, in partnership with BlindCAN.

Discover how Ora’s expert teams, proven processes, and advanced clinical approaches are accelerating ophthalmic research success around the globe. To connect with Ora at ARVO and learn more about our innovative ophthalmology clinical trial approaches and operational expertise, please reach out to us at OraBD@Oraclinical.com.

ARVO 2025 ORA RESEARCH PRESENTATION SCHEDULE

Title

Presenter

Date/Time

Presentation / Poster #

Automated Optokinetic Nystagmus Testing as an Objective Measure of Visual Acuity in Low Vision Populations

Keith Lane

May 4 - 1:00 PM to 2:45 PM

547 - A0108

A Hybrid Machine Learning Pipeline for Real-Time Automated Tracking of Patient Drop Compliance

Palak Gupta

May 5 - 8:30 AM to 10:15 AM

1577 - A0499

In-Vivo Confocal Microscopy of the Limbus Compared to Lissamine Green Staining Following Exposure to Controlled Adverse Environment

Paul Gomes

May 5 - 3:00 PM to 4:45 PM

1979 - A0077

Personalized Airflow Modulation in a Controlled Adverse Environment for Evaluating Ocular Surface Protection Mechanisms in Dry Eye Simulation

Ethan Bensinger

May 5 - 8:30 AM to 10:15 AM

1600 - A0522

Defining Drug Delivery Device Performance of Ophthalmic Blow-Fill-Seal (BFS) Ampoule Based Upon Physical Characteristics

Robert Whitfield

May 5 - 8:30 AM to 10:15 AM

1571 - A0493

Early Detection of Diabetic Maculopathy with Vanishing Optotypes

Palak Gupta

May 7 - 2:00 PM to 3:45 PM

4741 - A0067

Interblink Visual Acuity Decay with Automated Blink Detection in Dry Eye Disease

Ethan Bensinger

May 7 - 11:15 AM to 11:30 AM

Paper Session - 4050 [Ballroom C]

Categorization of Supraciliary Flow Assessed by Ultrasonic Biomicroscopy after Cilioscleral Interposition Device Implantation and its Relationship with Intraocular Pressure

Gus De Moraes

May 7 - 11:45 AM to 12:00 PM

Paper Session - 4076 [Ballroom G]

Advancing Compliance and Data Integrity in Clinical Trials: The Ora Digital Diaries System

Gus De Moraes

May 8 - 8:00 AM to 9:45 AM

5778 - B0374

Automated Detection and Classification of Limbal Lissamine Green Staining in Dry Eye subjects using a Novel Machine Learning Approach

Ethan Bensinger

May 8 - 8:00 AM to 9:45 AM

5638 - B0033

CAE-HT: A Rapid and Precise Challenge Model for Dry Eye Assessment

Matt Chapin

May 8 - 8:00 AM to 9:45 AM

5651 - B0046

Efficacy and Safety of PL9643 in Participants with Dry Eye Disease: Results from a Phase 3, Randomized, Vehicle-controlled Study

George Ousler

May 8 - 8:00 AM to 9:45 AM

5667 - B0062

About Ora

Ora is the world’s leading full-service ophthalmic drug and device CRO with employees in over 20 countries around the world. For over 50 years, we have proudly helped our clients earn more than 85 ophthalmic product approvals. We support a wide array of innovators and organizations, from start-ups to global pharmaceutical and device companies, to efficiently bring new products from concept to market. Ora’s unique methodologies, clinical models, and regulatory strategies have been refined and proven across thousands of global projects. For more information, please visit www.oraclinical.com and follow us on LinkedIn.


Contacts

Anne Marie Jedraszczak
ajedraszczak@oraclinical.com

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