DUSSELDORF, May 22 /PRNewswire/ -- International scientists in the field of molecular orthopaedics met for the 2nd Congress of the International Society for Molecular Orthopaedics (ISMO) in Dusseldorf, Germany. More than 100 members informed about new therapies against musculoskeletal diseases. "The meeting shows that basic research in molecular orthopaedics and new biological therapies change orthopaedic treatments and improve the clinical results," said Prof. Peter Wehling, MD, CEO of Orthogen AG.
The treatment of osteoarthritis (OA) with Orthokine(R) is now used frequently. Orthokine(R) contains anti-inflammatory cytokine antagonists and growth factors. A randomized double-blind trial with 400 patients demonstrated its high efficacy and safety. "Due to its beneficial side effect profile, Orthokine(R) represents an efficient alternative to steroids, hyaluronic acids and analgesics", said ISMO-President PD Axel W. A. Baltzer, MD (Center for Molecular Orthopaedics, Dusseldorf).
Prof. Christopher Evans, PhD Harvard Medical School, stated that gene therapy of Rheumatoid Arthritis (RA) is feasible and safe. This could be shown from the results from a long-term gene therapy study on nine women. The premise for a widespread clinical application is the use of in-vivo technology.
The regeneration of cartilage from non-embryonic stem cells is an important advance. Clinical results on ten patients demonstrated the feasibility and safety of this method. Orthogen AG licensed this novel stem cell technology exclusively from Harvard University. This new procedure is intended to replace time-consuming autologous chondrocyte implantation (ACI).
Prof. Paul Robbins, PhD University of Pittsburgh, presented a new immune-modulatory therapeutic approach using exosomes for the treatment of rheumatoid arthritis (RA). Exosomes are highly efficient anti-inflammatory nanoparticles. Clinical studies from the Center for Molecular Orthopaedics on 66 patients demonstrated this method's feasibility, efficacy and safety.
www.is-mo.orgwww.neue-orthopaedie.de Orthogen AG Antje Kassel Graf-Adolf-Str. 43 D-40210 Dusseldorf Tel.: +49(0)211-3870076 Fax: +49(0)211-3870010 E-Mail: antje.kassel@orthogen.comwww.orthogen.com
Orthogen AGCONTACT: Orthogen AG, Antje Kassel, Graf-Adolf-Str. 43, D-40210Düsseldorf, Tel.: +49(0)211-387-0076, Fax: +49(0)211-387-0010, E-Mail:antje.kassel@orthogen.com
