BOSTON--(BUSINESS WIRE)--Orthofix International N.V. (NASDAQ: OFIX) (the Company) announced today it sent a letter to its shareholders, which is included below, expressing concerns about Ramius, an activist hedge fund seeking to remove four current members of Orthofix’s Board of Directors and replace them with four of their own hand-picked nominees at a Special Meeting of Shareholders scheduled for April 2, 2009.