As a treatment for upset stomach, omeprazole, sold under the trade names Prilosec and Rapinex, provides superior relief to that achieved with ranitidine, sold as Zantac, or with cisapride, sold as Propulsid, Canadian researchers report in the American Journal of Gastroenterology.Omeprazole belongs to a drug group called protonpumpinhibitors, which alter the acidity of the stomach. Ranitidine also affects the acidity, but works by blocking the chemical histamine. Cisapride, by contrast, doesn’t affect the acidity directly, but rather improves the emptying of the stomach.