Novavax Hopes to Solve a Riddle that Has Puzzled Drugmakers for Decades

A Maryland-based biotech company believes it can solve a riddle that has baffled Big Pharma for decades: how to protect against a virus that infects almost every American child.

If mid-stage trial data proves positive, Novavax Inc will be closer than any drug developer to a vaccine for respiratory syncytial virus, or RSV, which affects those most with compromised immune systems - including young infants and the elderly.

An effective vaccine would represent a $1 billion opportunity in the United States and potentially double that worldwide, said Heather Behanna, an analyst at Wedbush Securities.

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