Nastech Pharmaceutical To Release Third Quarter Financial Results And Host Webcast On Wednesday, November 2, 2005

BOTHELL, Wash., Oct. 25 /PRNewswire-FirstCall/ -- Nastech Pharmaceutical Company Inc. , a leader in developing therapeutics using advanced molecular biology-based drug delivery technologies, announced today that its third quarter financial results will be released on Wednesday, November 2, 2005 after the Nasdaq National Market System closes. Management will host a conference call with investors and financial analysts to discuss these results and to provide an update to its clinical pipeline at 4:30 p.m. Eastern Time (1:30 p.m. Pacific Time).

To participate in the live conference call, U.S. residents should dial (800) 260-8140 and international callers should dial (617) 614-3672. The access code for the live conference call is 87570114. To access the 24-hour telephone replay, U.S. residents should dial (888) 286-8010 and international callers should dial (617) 801-6888. The access code for the replay is 19919215.

Alternatively, all interested parties are welcome to log on to www.nastech.com to access a live webcast or the subsequent 30-day archive. Please connect to the Investor section of Nastech’s website several minutes prior to the start of the live conference call to ensure adequate time for any software download that may be necessary.

About Nastech

We are a pharmaceutical company developing innovative products based on proprietary molecular biology-based drug delivery technologies. We and our collaboration partners are developing products for multiple therapeutic areas including inflammatory conditions, obesity and osteoporosis. Additional information about Nastech is available at www.nastech.com.

Contacts: Nastech Ed Bell Senior Investor Relations Manager (425) 908-3639 ir@nastech.com Noonan Russo Matthew Haines (Investors/Media) (212) 845-4235

Nastech Pharmaceutical Company Inc.

CONTACT: Ed Bell, Senior Investor Relations Manager of Nastech,+1-425-908-3639, ir@nastech.com; or Investors, Media - Matthew Haines ofNoonan Russo, +1-212-845-4235, for Nastech

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