Momenta Pharmaceuticals, Inc. Announces Nature Biotechnology Publication Demonstrating CHO Cells Can Produce Galactose-Alpha-1,3-Galactose Antigens on Proteins

CAMBRIDGE, Mass., Nov. 8, 2010 (GLOBE NEWSWIRE) -- Momenta Pharmaceuticals, Inc. (Nasdaq:MNTA), a biotechnology company specializing in the characterization and engineering of complex mixture drugs, today announced that the scientific journal Nature Biotechnology has published a correspondence entitled "Chinese Hamster Ovary Cells Can Produce Galactose-alpha-1,3-Galactose Antigens on Proteins." The studies, led by scientists at Momenta Pharmaceuticals, demonstrate that Chinese Hamster Ovary (CHO) cells contain the active biosynthetic machinery to produce alpha-Gal antigens and that a therapeutic protein manufactured in CHO contains alpha-Gal. Prior to these findings, it was believed that CHO cells lacked the biosynthetic machinery necessary to synthesize glycoproteins with these carbohydrate antigens.
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