Metabasis Therapeutics, Inc. To Host Conference Call And Live Webcast To Discuss Fourth Quarter And Year End 2006 Financial Results

SAN DIEGO, Feb. 22 /PRNewswire-FirstCall/ -- Metabasis Therapeutics today announced that the Company will host a conference call and live webcast on Thursday, March 8 at 1:30 p.m. Pacific Time to discuss its financial results for the fourth quarter of 2006. Dr. Paul Laikind, president and chief executive officer, Mr. John Beck, senior vice president of finance and chief financial officer, and Dr. Howard Foyt, vice president of clinical development, will participate in the call.

The conference call may be accessed by dialing 888-396-2386 for domestic callers and 617-847-8712 for international callers. Please specify to the operator that you would like to join the “Metabasis Fourth Quarter and Year End 2006 Financial Results Conference Call.” The conference call will be webcast live on the Metabasis website at www.mbasis.com, under the Investors section, and will be archived there for 30 days following the call. Please connect to Metabasis’ website several minutes prior to the start of the call to ensure adequate time for any software download that may be necessary.

About Metabasis (www.mbasis.com):

Metabasis Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of novel drugs to address some of the world’s most widespread and costly chronic diseases. The Company has established a pipeline that includes clinical stage and preclinical product candidates targeting major diseases with significant unmet medical needs. Targeted diseases include major metabolic diseases such as diabetes, hyperlipidemia and obesity as well as liver diseases such as hepatitis and primary liver cancer. Metabasis has developed several proprietary technologies for use in discovering and optimizing drugs, including the NuMimetic(TM) and HepDirect(R) technologies. Metabasis is continuing to identify and develop new product candidates using its proprietary technologies and expertise.

Contact: Constance Bienfait Vice President Investor Relations & Corporate Communications Metabasis Therapeutics, Inc. (858) 622-5575

Metabasis Therapeutics

CONTACT: Constance Bienfait, Vice President, Investor Relations &Corporate Communications of Metabasis Therapeutics, Inc., +1-858-622-5575

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