Metabasis Therapeutics, Inc. To Host Conference Call And Live Webcast To Discuss Fourth Quarter And Year End 2005 Financial Results

SAN DIEGO, March 9 /PRNewswire-FirstCall/ -- Metabasis Therapeutics today announced that the Company will host a conference call and live webcast on Thursday, March 23, 2006 at 1:30 p.m. Pacific Time to discuss its financial results for the fourth quarter and year end 2005. Dr. Paul Laikind, chairman, CEO and president, Mr. John Beck, senior vice president of finance and CFO, and Dr. Mark Erion, executive vice president of research and development, will participate in the call.

The conference call may be accessed by dialing 800-706-7741 for domestic callers and 617-614-3471 for international callers. Please specify to the operator that you would like to join the “Metabasis Fourth Quarter and Year End 2005 Financial Results Conference Call.” The conference call will be webcast live on the Metabasis website at www.mbasis.com, under the Investors section, and will be archived there for 30 days following the call. Please connect to Metabasis’ website several minutes prior to the start of the call to ensure adequate time for any software download that may be necessary.

About Metabasis (www.mbasis.com):

Metabasis Therapeutics is a biopharmaceutical company focused on the discovery, development and eventual commercialization of novel drugs to address some of the world’s most widespread and costly chronic diseases involving pathways in the liver. The Company has established a pipeline that includes clinical stage and preclinical product candidates targeting major diseases with significant unmet medical needs. Targeted diseases include major metabolic diseases such as diabetes, hyperlipidemia and obesity as well as liver diseases such as hepatitis and primary liver cancer. Metabasis has developed several proprietary technologies for use in discovering and optimizing drugs, including the NuMimetic(TM) and HepDirect(TM) technologies. Metabasis is continuing to identify and develop new product candidates using its proprietary technologies and expertise.

Metabasis Therapeutics, Inc.

CONTACT: Paul Laikind, Ph.D., Chairman, CEO & President of MetabasisTherapeutics, Inc., +1-858-622-5550

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