LIVINGSTON, N.J.--(BUSINESS WIRE)--Columbia Laboratories, Inc. (Nasdaq: CBRX) announced today that a meta-analysis of data from five double-blind, placebo-controlled trials of vaginal progesterone, including the PREGNANT study, Columbia's pivotal clinical trial of progesterone vaginal gel 8% to reduce the risk of preterm birth in women with premature cervical shortening, found that administering vaginal progesterone to asymptomatic women with a sonographic short cervix in the mid-trimester of pregnancy significantly reduces the risk of preterm birth and neonatal morbidity.