Little-Known Bits of RNA Help Master Tumor-Suppressor Gene Do its Job, University of Michigan Health System Cancer Researchers Find

ANN ARBOR, MI – Scientists have shown in literally thousands of studies that the p53 gene deserves its reputation as “the guardian of the genome.” It calls to action an army of other genes in the setting of varied cell stresses, permitting repair of damaged DNA or promoting cell death when the cell damage is too great. A key net effect of p53’s action is to prevent development of cancerous cells.

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