IRVINE, CA, and LAUSANNE, Switzerland, Jan. 25 /CNW/ - Further to the press releases dated 6 November 2006, 1, 14 and 15 December 2006, 22 January 2007 and the offer memorandum of 14 December 2006 (the “Offer Memorandum”), IsoTis Inc. and IsoTis SA (“IsoTis” or the “Company”) announce that IsoTis Inc. declares the public exchange offer (the “Exchange Offer”) for all issued and outstanding registered shares (the “IsoTis Swiss Shares”) unconditional. Unless defined herein, defined terms used in this announcement shall have the meaning ascribed to them in the Offer Memorandum.