NEW YORK, March 5, 2007 - When the results of a major long-term, multicenter study, the Trial of Preventing Hypertension (TROPHY), were called into question in two editorials published in the November 2006 issue of the American Journal of Hypertension (AJH), it was inevitable that an exchange of views between the study’s supporters and detractors would occur. The essential issue is whether the TROPHY data support the conclusions reported in the New England Journal of Medicine. The March issue of the American Journal of Hypertension publishes a response from TROPHY study investigators Stevo Julius, MD, ScD, Brent M. Egan, MD, and M. Anthony Schork, PhD, defending the work, while authors of the original AJH editorials, Dr. Stephen Persell, Dr. David W. Baker and Dr. Jay I. Meltzer provide further information to support their earlier observations and indicate that their original criticisms remain unaddressed.>>> Discuss This Story