CAMBRIDGE, Mass.--(BUSINESS WIRE)--Helicos BioSciences (Nasdaq:HLCS) today announced the release of transcriptome sequencing (RNA-Seq) datasets on the HeliSphere™ Technology Center (http://open.helicosbio.com), the company’s open access Web site for sharing Helicos datasets and bioinformatics software tools. Helicos’s amplification and ligation-free approach virtually eliminates the creation of false-positive splicing and fusion events, frequently observed in other RNA-Seq datasets.