FRAMINGHAM, Mass.--(BUSINESS WIRE)--GTC Biotherapeutics, Inc. (“GTC”, Nasdaq: GTCB) has entered into an extended agreement with PharmAthene, Inc. (Amex: PIP) under which GTC will provide continuing process development and clinical supply manufacturing services for PharmAthene’s Protexia® program. The manufacturing work is planned to conclude in the third quarter of 2008. Protexia® is a recombinant form of human butyrylcholinesterase (rBChE) produced in the milk of transgenic goats, which is being developed by PharmAthene as a pre- and post-exposure therapy for victims of a chemical nerve agent attack.