Generex Biotechnology Corporation to Test Novel RNAi-Based Immune-Response Strategy in Cancer Patients

TORONTO -- (MARKET WIRE) -- March 26, 2007 -- Generex Biotechnology Corporation (NASDAQ: GNBT) announced today that its Antigen Express subsidiary has entered into an agreement with Beijing Daopei Hospital in Beijing, China to conduct clinical trials on a novel immunotherapeutic strategy using the Company’s proprietary methods of RNAi stimulation of the immune response against the patients’ immune cells. The trials will be conducted under the direction of Dr. Daopei Lu. Dr. Lu was the first to perform bone marrow transplantations in China, has been involved in many clinical trials, and has authored over 200 articles in peer-review journals. RNAi (RNA interference) refers to the introduction of homologous double stranded RNA (dsRNA) to specifically target a gene’s product, resulting in null or hypomorphic phenotypes. The technology is being viewed as a possible groundbreaking improvement over current therapies, such as chemotherapy for cancer, which uses a broad stroke method, destroying the cancer cells but damaging healthy cells in the process.

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