In the course of examining the Drosophila tumor suppressor gene (Dlg), scientists at the Helmholtz Zentrum München have succeeded in decoding a new mechanism that regulates cell polarity in epithelial tissues or in neurons in the brain. The findings, which are presented in the current issue of Developmental Cell, will help to enhance the understanding of how metastases and mental retardation occur and enable targeted, long-term therapeutic approaches to their treatment to be developed.
