The drug prasterone is a safe and effective treatment for lupus, says a study in the September issue of Arthritis & Rheumatism.Prasterone is the pharmaceutical form of DHEA (dehydroepiandrosterone), a natural steroid hormone produced by the adrenal glands of both women and men.Lupus is a serous immune system disease that causes symptoms such as fatigue, rash and arthritis. Women are nine times more likely than men to have lupus. Researchers have found women with lupus have abnormalities in the metabolism of two hormones -- androgen and estrogen.This year-long, multi-center trial included 381 women with active lupus. About half received 200 milligrams of prasterone a day while the other group received the same daily dose of a placebo. Women in both groups were allowed to continue their course of standard lupus medications.
