FREMONT, Calif.--(BUSINESS WIRE)--DiscoveRx announced today the release of the most detailed comprehensive assessment of interaction profiles of known kinase inhibitors across the kinome published to date in the November 2011 issue of Nature Biotechnology, titled “Comprehensive analysis of kinase inhibitor selectivity.” This seminal publication utilizing the KINOMEscan platform, wholly-owned by DiscoveRx Corporation, in collaboration with Ambit Biosciences®, quantitatively assessed the interaction patterns of 72 kinase inhibitors against 442 kinases, and included all major kinase groups plus a panel of 54 clinically relevant mutants and several activation state-specific ABL assay pairs. This work expands on their 2008 research publication, recently hailed by Nature Biotechnology as one of the most cited research publications during the period 2006 to 2011.
