SOUTH SAN FRANCISCO, CA--(Marketwire - June 16, 2008) - Cytokinetics, Incorporated (NASDAQ: CYTK) announced positive results today from an interim analysis of an ongoing Phase IIa clinical trial evaluating CK-1827452, a novel cardiac myosin activator, administered intravenously to patients with stable heart failure. These results were presented at the Late Breaking Trials Session at the Heart Failure Congress, the annual meeting of the Heart Failure Association of the European Society of Cardiology in Milan, Italy. A presentation entitled, “The Selective Cardiac Myosin Activator, CK-1827452, Increases Systolic Function in Heart Failure,” was made by John Cleland, MD, FACC, FRCP, FESC, Professor of Cardiology, Castle Hill Hospital, University of Hull, United Kingdom. CK-1827452 is being developed as a potential treatment for patients with either acutely decompensated or chronic heart failure. CK-1827452 is being developed in connection with a strategic alliance between Cytokinetics and Amgen.
