CuraGen Corporation To Discuss First Quarter 2006 Results Via Conference Call On April 27, 2006

BRANFORD, Conn., April 20 /PRNewswire-FirstCall/ -- CuraGen Corporation today announced that Company executives will be holding a conference call to discuss CuraGen’s first quarter 2006 results at 11:00 a.m. Eastern time on Thursday, April 27, 2006. Dr. Frank M. Armstrong, President and Chief Executive Officer of CuraGen, will be hosting the conference call. A press release outlining first quarter 2006 results will be issued prior to the call.

Date: Thursday, April 27, 2006 Time: 11:00 a.m. ET Dial-in: 877-272-5391 (domestic) 706-758-4315 (international) Passcode: 8049670

Webcast: Access to the live webcast is available on CCBN and at http://www.curagen.com.

A replay of the conference call will be available starting at 2:00 p.m. Eastern time on Thursday, April 27, 2006 through Saturday, May 27, 2006 by dialing 800-642-1687 (domestic) or 706-645-9291 (international). The passcode for the replay is 8049670. An archive of the webcast will be available for 30 days at http://www.curagen.com.

About CuraGen

CuraGen Corporation is a biopharmaceutical company developing diverse approaches, including novel protein, antibody, and small molecule therapeutics, that aim to offer hope for patients with cancer, inflammatory diseases, and diabetes. CuraGen’s strategic alliances have resulted in a deep pipeline of therapeutics that is being developed by the Company’s experienced research and development teams. By leveraging the drug development strength’s cultivated over the years, CuraGen expects to make a difference in the lives of patients by bringing forward promising therapeutics that address unmet medical needs. CuraGen is headquartered in Branford, Connecticut. For additional information please visit http://www.curagen.com.

Contact: Glenn Schulman, Pharm.D. Assistant Director of Investor Relations gschulman@curagen.com (888) 436-6642

CuraGen Corporation

CONTACT: Glenn Schulman, Pharm.D., Assistant Director of InvestorRelations at CuraGen Corporation, +1-888-436-6642, gschulman@curagen.com

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