As a leading customer service provider with extensive experience in the field of antibody engineering, Creative Biolabs successfully developed all three types of bispecific antibodies with well-established methods to fulfil the market demands.
Bispecific antibodies (BsAbs) are bioengineered antibodies that contain two different binding sites within a single molecule, which can specifically bind two different types of antigens. The most widely used application of bi-specific antibody is in cancer immunotherapy which creates a therapeutic treatment approach for diseases with specific medical needs.
With the development of antibody engineering, many types of bispecific antibodies have been designed to enable short half-life, immunogenicity and side-effects led by cytokine liberation, including tri-functional antibodies, chemically linked Fabs and various types of bivalent and trivalent single-chain variable fragments (scFvs), fusion proteins mimicking the variable domains of two antibodies. The latest developed of these newer formats are the bi-specific T-cell engagers (BiTEs) and mAb2’s, antibodies engineered to contain an Fcab antigen-binding fragment instead of the Fc constant region.
Creative Biolabs offers various bispecific antibodies, such as tri-functional antibodies and chemically linked Fabs, bivalent,and Bispecific scFvs (tandem scFv, diabodies), bi-specific T-cell engagers (BiTEs) and scFv-Fab fusion proteins.
About Creative Biolabs
Throughout the years, Creative Biolabs has developed itself a great force in the field of antibody production and engineering. Established by a group of scientists who are committed to conquering cancer, Creative Biolabs focuses its business model on improving and enhancing the R&D of beneficial drugs and leveraging all accessible resources.
Creative Biolabs’ service portfolio includes antibody production in rats and mice through the use of hybridoma technology, as well as rabbit, chicken, dog, camel, llama, monkey and human antibody production through the use of various antibody library technologies, including yeast display, bacterial display and phage display.
Creative Biolabs aims to change the world by fighting against cancer and providing research required to overcome such life-threatening illnesses. Depending on its expertise in antibody production and antibody manufacturing, its long-term goal is to deliver the highest quality of services in all areas of its field.
