A surprisingly large subset of depressed patients (10-15%) develop psychotic symptoms such as hallucinations and delusions. Not only are these patients seriously depressed, they are highly suicidal and have an increased incidence of homicides. There is mounting evidence that this psychotic state is caused by a disturbance in cortisol levels. Corcept, Inc. takes aim at the source of the problem with its new Corlux (mifepristone) treatment currently in Phase III trials…
