DENVER--(BUSINESS WIRE)--Ceragenix Pharmaceuticals, Inc. (OTCBB:CGXP) (the “Company”), a biopharmaceutical and medical device company focused on infectious disease and dermatology, today announced that preclinical testing of the Company’s CeraShield™ coated endotracheal tubes and C.R. Bard’s recently FDA cleared Agento™ tube has shown that Cerashield™ coated endotracheal tubes were able to provide a 7 fold increase in the duration of antimicrobial protection compared to the recently cleared silver coated Agento™ tube from C.R. Bard. The CeraShield™ coated endotracheal tube was able prevent bacterial colonization and biofilm development for 21 days while C.R. Bard’s Agento™ endotracheal tubes lost their ability to prevent bacterial colonization and biofilm development after 3 days when challenged with daily high inocula (10E6) of Pseudomonas aeruginosa. Bacterial growth on endotracheal tubes is a key component in the pathogenesis of Ventilator Associated Pneumonia (“VAP”) which afflicts an estimated 250,000 patients each year and is associated with high morbidity ( 36,000 deaths) and added hospital costs of $4 billion in the U.S. alone. The testing was conducted by Dr. Paul B. Savage’s laboratory at Brigham Young University (“BYU”). Cerashield™ has not been cleared by the U.S. Food and Drug Administration for use in the United States or by any international regulatory agency.
