NEW YORK--(BUSINESS WIRE)--Centinel Spine, Inc. (Centinel), a market leader in the development, manufacture and distribution of Integrated Interbody Fusion™ devices, today announced a record 41.8% revenue increase during the 4th quarter, 2010, vs. 3rd quarter, 2010. Also, during the 4th quarter, 2010, Centinel achieved a record setting 32.5% gain vs. the same period in 2009.