The Boston Globe Names Cubist Pharmaceuticals, Inc. to Top Places to Work 2010

Lexington, Mass., November 8, 2010 -- Cubist Pharmaceuticals, Inc. (NASDAQ: CBST) today announced that it has been named one of the Top Places to Work in Massachusetts in the third annual employee- based survey from The Boston Globe. Cubist has been named to the list all three years. This year the rankings were organized into three categories: Large, Midsize, and Small companies. Cubist was ranked 24th in the Midsize category and was the highest ranking public life-sciences company in its category. The Boston Globe Top Places to Work 2010 magazine was published in the Sunday Globe on November 7. Online, the report can be found at www.boston.com/topworkplaces.

Produced by the same team that compiles the 23-year-old Globe 100 report of the best-performing public companies in Massachusetts, where Cubist ranked number 23 this year, the Top Places to Work recognizes the most progressive companies in the state based on employee opinions about company leadership, compensation and training, diversity/inclusion, career development, family-friendly flexibility, and values and ethics. Private companies and nonprofits as well as publicly-held businesses were included in the analysis.

The Globe invited 1,160 employers to participate in the third annual Top Places to Work. Of those, 236 organizations went all the way through the process. Research partner WorkplaceDynamics of Exton, Pa., specialists in employee engagement and retention, contacted more than 133,000 employees at those companies, and received completed surveys from 82,000 individuals. Each was asked to grade their organization’s performance according to 23 distinct statements, ranging from “This organization demonstrates it values employees during difficult times ’’ to “It’s easy to tell my boss the truth.’’

Cubist President and CEO Michael Bonney said, “We are gratified to be among the best in Massachusetts as measured in the Boston Globe Top Places to Work survey. Our inclusion on the list is a reflection of our employees’ feedback. We are committed to providing an environment where our high-performing employees experience a high degree of workplace satisfaction, while building the world’s leading company focused on providing therapies for acutely ill patients. To ensure that mission’s success, we depend on retaining and attracting the best and most highly motivated and committed scientific and business personnel.”

The publisher of The Boston Globe Chris Mayer stated, “Each of the companies included in the Top Places to Work 2010 deserve recognition for creating a positive workplace for their employees. Their accomplishment adds to the vitality of this state’s business environment.”

To qualify for the Boston Globe’s Top Places to Work, a company must have more than 100 employees in Massachusetts. Rankings were based on composite scores calculated purely on the basis of employee responses.

About Cubist

Cubist Pharmaceuticals, Inc. is a biopharmaceutical company focused on the research, development, and commercialization of pharmaceutical products that address unmet medical needs in the acute care environment. In the U.S., Cubist markets CUBICIN® (daptomycin for injection), the first antibiotic in a class of anti-infectives called lipopeptides. The Cubist clinical product pipeline currently consists of a Phase 2 program focused on the development of a novel cephalosporin to address certain serious infections caused by multi-drug resistant (MDR) Gram-negative organisms; and a Phase 2 program for the treatment of CDAD (Clostridium difficile-associated diarrhea). Cubist is also working on several pre-clinical programs being developed to address areas of significant medical needs. These include an anti-infective program for the treatment of respiratory syncytial virus (RSV) in children, therapies to treat various serious bacterial infections, and agents to treat acute pain. Cubist is headquartered in Lexington, Mass. Additional information can be found at Cubist’s web site at www.cubist.com.

Cubist and CUBICIN are registered trademarks of Cubist Pharmaceuticals, Inc.

Contacts:

Cubist Pharmaceuticals, Inc. Weber Shandwick Eileen C. McIntyre Tara Murphy Senior Director, Corporate Communications (617) 520-7045 (781) 860-8533 tara.murphy@webershandwick.com eileen.mcintyre@cubist.com

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