David Bagley Joins Histogen, Inc. as President

SAN DIEGO, January 14, 2009 - Histogen, Inc., a regenerative medicine company developing solutions based on the products of newborn fibroblasts, announced today that David Bagley has joined the Company as President. Histogen welcomes Bagley following a year of rapid growth, with product launches, clinical evaluations and a new facility move on the horizon.

“With the launch of Histogen’s first product, the creation of an aesthetics division, and talented new members joining the team in 2008, we’ve laid the groundwork for exciting progress in the coming year,” said Dr. Gail Naughton, Histogen CEO and Chairman of the Board. “I am pleased to welcome David Bagley to Histogen, and believe his business experience and background in the field of tissue engineering will be a great asset to Histogen as we move forward.”

David Bagley brings more than 20 years of cell biology and tissue engineering industry experience to Histogen. He has been a contributor to operational, scientific and engineering advancements in the development of several technologies including cell culture, tissue engineered and cell-based products for the treatment of multiple critical diseases, wound care and aesthetic product applications.

Most recently, Bagley served as Vice President and General Manager for Allergan Medical, Inc. with a focus on operations, technology, global distribution, quality and business disciplines. Prior to this, he held positions with Smith + Nephew/Advanced Tissue Sciences for over 12 years, where his latest position was Vice President of Technology and Logistics.

Previously, Bagley worked for Sigma Chemical Company where he was involved in the development and launch of several tissue culture product lines. Early in his career, he worked for HyClone Laboratories and Clonetics, both manufacturers and providers of cell culture products for various markets. Bagley has a B.S. degree in biology from Utah State University and a Master’s degree in business from the American Graduate School of International Management in Arizona.

“Tissue engineering and cell-based products show a great deal of promise in the treatment of critical diseases and improving the lives of many people, however the development and launching of these complex products can be a challenge,” said Bagley. “I am excited to join Histogen as President, and look forward to progressing these products and technologies to market.”

About Histogen

Histogen, launched in 2007, seeks to redefine regenerative medicine by developing a series of high value products without the use of embryonic stem cells or animal products. Through Histogen’s proprietary bioreactors that mimic the embryonic environment, newborn fibroblasts are encouraged to naturally produce the vital proteins and growth factors from which the company has developed its rich product portfolio. Histogen has two product families - ExceltrixTM, Histogen’s human Extracellular Matrix (ECM) and ReGenicaTM, Histogen’s proprietary liquid formula. The Company recently launched its first product – BioNuesisTM Human Stem Cell Culturing Kits – and announced the creation of its cosmeceutical venture – Histogen Aesthetics. For more information, please visit www.histogeninc.com.

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