Patent Issued for Multiomic Approach to Autism Spectrum Disorder Diagnosis
SYRACUSE, N.Y., Feb. 28, 2022 /PRNewswire/ -- Quadrant Biosciences Inc. announced today that the United States Patent and Trademark Office (USPTO) has issued the company and its partners, the SUNY Research Foundation and Penn State Research Foundation, U.S Patent No. 11,242,563 (Analysis of Autism Spectrum Disorder). The patent covers the scientific foundation for the development of a saliva-based, multiomic autism diagnostic aid, that can differentiate individuals with autism from individuals with typical development or developmental delays by measuring microRNA (miRNA) and microbiome levels in saliva. Quadrant Biosciences, a Life Science company based in Syracuse, New York, leverages next generation sequencing and AI to develop RNA-based molecular diagnostics for a range of medical conditions.
"The issuing of an official US patent for our work on development of a saliva-based diagnostic aid for autism is a clear acknowledgement of the novelty and utility of the approach that we developed," said Frank Middleton, PhD, Professor at SUNY Upstate Medical University and one of the principal investigators behind the patented research. "Our focus on deploying a multiomic approach that combines regulatory RNA features from the human host as well as the oral microbiome has yielded considerable insight into autism spectrum disorder."
Dr. Steve Hicks, MD, PhD from Penn State College of Medicine, the other key inventor on the patent, explained its potential clinical significance. "We hope this molecular tool will enhance the ability of clinicians to distinguish children on the autism spectrum from peers with non-autistic developmental delay, enabling earlier diagnoses and earlier initiation of behavioral therapy. Moreover," he continued, "this milestone validates the inherent innovation in Quadrant Biosciences' research and advances our collective goal of improving medical care for children with autism spectrum disorder."
"We are delighted that the USPTO has granted our patent for this groundbreaking work," said Rich Uhlig, Founder and CEO of Quadrant Biosciences. "This supports our years of rigorous R&D efforts to illuminate the epigenetic factors associated with autism, and develop novel diagnostic biomarkers to address the urgent need to shorten the protracted autism diagnostic odyssey for parents and caregivers."
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SOURCE Quadrant Biosciences Inc.