Hemogenyx Pharma Release: LakePharma Appointed As Service Provider for Lead Drug Development
LONDON, UNITED KINGDOM -- (Marketwired) -- Oct 30, 2017 -- HemoGenyx (
The relationship between Hemogenyx Pharmaceuticals and LakePharma is designed to have a seamless product development process, from discovery to biomanufacturing, as Hemogenyx moves its cutting-edge therapies toward clinical trials. Strategically, the formalization of this relationship is particularly significant because it marks a major step in the pre-clinical development of Hemogenyx's CDX antibodies. Undertaken with the expertise and validated technology of LakePharma, the largest US-based biologics contract research organization, this step brings Hemogenyx significantly closer to its goal of taking the CDX antibodies into clinical trials at the earliest opportunity with a faster path through pre-clinical trials.
Dr. Vladislav Sandler, CEO of Hemogenyx, said: "After a thorough evaluation process, we chose to partner with LakePharma for the development and manufacture of CDX antibodies for preclinical tests. The speed, quality and sophistication of LakePharma's services gives us confidence that we will go into clinical trials on time with a reliable product that will eventually save lives."
Dr. Hua Tu, Founder and CEO of LakePharma, commented: "LakePharma has been providing antibody engineering and bioproduction service to Hemogenyx for several years and helped them to create the underlying IP for their CDX technology. We are pleased to see that LakePharma's one-stop-shop capabilities can be applied towards Hemogenyx's breakthrough product development."
Hemogenyx has achieved proof of principle for the use of CDX antibodies to condition patients for bone marrow transplant and anticipates beginning clinical trials of the therapy within 18 months. Already, Hemogenyx has functionally validated CDX bi-specific antibodies in vitro and in vivo in humanized mouse models. It is anticipated that the CDX bi-specific antibodies will be capable of use as an "off-the-shelf" conditioning product available for application for all BM/HSC transplantations that require conditioning.
Blood cancers affect more than 1.1 million people in the United States each year, and it is estimated that 171,500 new blood cancer diagnoses were made in 2016. Hemogenyx seeks to fundamentally change how patients are conditioned before transplantation. Currently, patients receive chemotherapy and radiation treatments before transplant. These preparative regimens are toxic and non-selective, resulting in severe side effects that can be life-threatening or lead to complications including radiation damage, fertility issues, bone damage and bone growth problems.
Hemogenyx Pharmaceuticals Limited http://www.hemogenyx.com/ Dr Vladislav Sandler, Chief Via Walbrook PR Executive Officer & Co-Founder Dr Robin Campbell, Chairman Optiva Securities Ltd Tel: +44 (0)20 3137 1902 Christian Dennis Shard Capital Partners LLP Tel: +44 (0)20 7186 9950 Damon Heath, Erik Woolgar Peterhouse Corporate Finance Tel: +44 (0)20 7469 0930 Limited Lucy Williams/Duncan Vasey Walbrook PR Tel: +44 (0)20 7933 8780 or firstname.lastname@example.org Paul McManus Mob: +44 (0)7980 541 893 Flowcomms IR Mob: +44 (0)7891 627 441 or email@example.com Sasha Sethi
About Hemogenyx Pharmaceuticals Plc
RNS Customer Services 0044-207797-4400 firstname.lastname@example.org http://www.rns.com