Carnegie Mellon Scientists Use Atomic Force Microscopy To Discover Effects Of Experimental Alzheimer's Drugs On Plaque Formation

Scientists at Carnegie Mellon University have used atomic force microscopy (AFM) to shed light on molecular scale processes underlying the formation of insoluble plaques associated with Alzheimer's Disease. Results of this work suggest that AFM could lead to a better understanding of the disease process and help guide the search for new diagnostic and treatment approaches. The report will be published in the Jan. 23 issue of the Journal of Molecular Biology and appears online at www.sciencedirect.com/web-editions/journal/00222836. Supported by the National Institutes of Health, the research was done in collaboration with scientists at Eli Lilly and Company and the Washington University School of Medicine.

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